Design Expert - Introduction

Course: Quality by Design (QbD) – Statistical Experimental Design for Pharmaceutical Processes Quality by Design (QbD) is the FDA-recommended method for developing and optimizing pharmaceutical products and processes. The central idea is to define factor spaces within which consistent product quality is ensured. Once a design space is approved by regulatory authorities, the process can be adjusted within these limits without requiring re-approval. This methodology provides new flexibility in the production of pharmaceutical products and medical devices, reducing regulatory hurdles. What You Will Learn in This Course: 📌 Fundamentals of Quality by Design (QbD) & Design of Experiments (DoE) 📌 Statistical Tools: Hypothesis Testing & Regression Analysis 📌 Screening Designs: Efficiently Identifying Key Factors 📌 Response Surface Designs: Defining and Optimizing Design Spaces 📌 Validation of Design Spaces for Regulatory Approval 📌 Practical Implementation with Design-Expert® Software The course will follow a complete QbD cycle using FDA examples and statistically model it with Design-Expert® software. Requirements: 📌 Basic knowledge of Design-Expert® is beneficial. 📌 Knowledge of regression analysis and hypothesis testing is helpful but not required. 🕒 Course Duration: 3 Days 🔹 Sign up now and optimize your pharmaceutical development!

Course: Experimental Design for Mixture Experiments with Design-Expert® In this two-day course, you will learn how to apply statistical experimental design specifically for mixture experiments. Traditional experimental designs are unsuitable for formulation and mixture optimization — instead, mixture designs are needed. This course will provide you with comprehensive knowledge of powerful mixture experimental designs, from creation to graphical analysis and optimization of formulations. You will work with the software Design-Expert® to efficiently create and analyze mixture designs. Why Mixture Experiments? 🔹 Optimizing formulations with multiple components 🔹 Specialized mixture designs for realistic formulations 🔹 Statistical & graphical analysis methods for precise evaluations 🔹 Practical implementation in Design-Expert® with real-world examples Course Content: ✅ Creating & Analyzing Simplex Designs ✅ Selecting suitable mixture designs & models ✅ Generating contour plots in the triangular experimental region ✅ Creating mixture designs with constraints ✅ Optimizing product compositions & formulations ✅ Evaluating design quality & expanding designs ✅ Creating contour diagrams & trace plots for detailed analysis Requirements: 📌 Basic knowledge of experimental design with factorial designs — ideally at the level of the course “Introduction to Experimental Design with Design-Expert®”. 🔹 Sign up now and take your formulation optimization to the next level!

Two-Day Course: Process and Product Optimization with Response Surface Methodology (RSM) In this intensive two-day course, you will learn how to efficiently optimize processes and products using Response Surface Methodology (RSM). This method goes beyond factorial designs and allows for the best possible adjustment of influencing factors to achieve optimal results. Why Response Surface Methodology (RSM)? 🔹 Ideal for complex optimization tasks where factorial designs are insufficient 🔹 Determine optimal factor settings for product and process optimization 🔹 Create models for response surfaces to perform simulations and define process windows 🔹 Use Design-Expert® software to easily and efficiently create RSM designs Course Content: ✅ Expanding factorial designs with center-point runs ✅ Creating RSM experimental designs such as Central Composite Designs (CCD) & Box-Behnken Designs ✅ Selecting appropriate regression models for precise analysis ✅ Determining robust computational conditions to improve process stability ✅ Simultaneously optimizing multiple objectives for comprehensive results ✅ Evaluating design quality to ensure reliable data Requirements: 📌 Basic knowledge of statistics and experimental design with factorial designs is helpful — ideally at the level of the course “Introduction to Experimental Design with Design-Expert®.” 🔹 Sign up now and elevate your optimization skills to the next level!

🚀 Stat-Ease 360® – The Next Generation of Design of Experiments (DoE) Software Stat-Ease 360 is the most advanced statistical software from the makers of Design-Expert®, offering a powerful extension to the renowned DoE platform. Built for engineers, scientists, and analysts, Stat-Ease 360 delivers cutting-edge tools for design of experiments, data analysis, and automation – all within a user-friendly interface. ✅ Why Choose Stat-Ease 360? ✔ Includes all features of Design-Expert® – and more ✔ Seamless Python integration for automation, scripting, and database connectivity ✔ Enhanced DoE tools for simulation-based experiments ✔ Supports Gaussian Process Models, Latin Hypercubes, and model-based optimal designs ✔ Maintains the intuitive user interface of Design-Expert® Whether you're optimizing physical experiments or running computational simulations, Stat-Ease 360 (SE360) provides the tools to boost precision, reduce resource usage, and streamline your workflow. 🔍 New Features in Stat-Ease 360 🔹 Logistic Regression with ROC Curves Perform advanced classification analyses with visual ROC curve output for clear, data-driven decision-making. 🔹 Simulation-Optimized Designs Leverage space-filling designs and modern modeling techniques for accurate computer-based experiments. 🔹 Gaussian Process Modeling Incorporate powerful surrogate modeling tools to better interpret and optimize simulation responses. 🔹 Latin Hypercube Sampling (LHS) Create space-filling designs that efficiently explore the input space of complex models. 🔹 Python Scripting Integration Automate data analysis, connect to external databases, and expand your capabilities with Python libraries and APIs. 👨‍🔬 Designed for Advanced Experimental Analysis Stat-Ease 360 is ideal for: Engineers & Researchers working on simulation and optimization Data Scientists integrating experimental models into Python workflows Product Developers needing faster, smarter insights Six Sigma, R&D, and Quality Teams aiming for data-driven decision-making 🎯 Key Benefits ✅ Full compatibility with Design-Expert® projects ✅ Enhanced tools for simulation, modeling & machine learning workflows ✅ Scalable from small lab tests to high-performance simulations ✅ Modern statistical features with an intuitive interface 📥 Try Stat-Ease 360 for Free! Discover how SE360 can transform your DoE workflows and simulation strategies. ➡ Download the free trial and experience the future of experimental design: 👉 Trial-version

Design-Expert® – The User-Friendly Software for Design of Experiments (DOE) Design-Expert is a powerful design of experiments (DOE) software that combines an easy-to-use, intuitive interface with the latest techniques in multifactorial data analysis. The software guides you through all classic DOE phases: screening, optimization (RSM), and validation. With Design-Expert, you save time and costs in product development while improving process conditions. Why Choose Design-Expert? ✅ Interactive 3D visualizations & contour plots – Quickly and easily identify optimization potential ✅ Versatile experimental designs – From classic designs to split-plot and mixture designs ✅ Multivariate optimization – Optimize multiple response variables simultaneously ✅ Excel export – Objective functions can be exported directly as formulas ✅ Propagation of error analysis – Find robust settings for your processes Features of Design-Expert 📊 Rotatable 3D surface plots – Perfect for visualizing response surfaces 📊 Interactive contour & ternary plots – For precise process and formulation optimization 📊 All classic design types – Including D-optimal screening designs and I-optimal designs for RSM 📊 Definitive screening & split-plot designs – Ideal for hard-to-change factors 📊 Mixture & combined designs – Perfect for chemistry, pharmaceuticals, and formulation development 📊 Optimization platform with numerical optimization – Automatically calculates the best factor settings Perfect for: ✔️ Research & Development ✔️ Chemical and pharmaceutical applications ✔️ Process optimization & quality control ✔️ Formulation & recipe development Download Design-Expert® – Free Demo! Try Design-Expert, the powerful DOE software, for free! The trial version is available for download on the Stat-Ease website. 🔹 Test all features – Experience the full power of screening, optimization (RSM), and validation 🔹 Intuitive user interface – Simple operation for fast results 🔹 Optimize formulations & processes – Ideal for research, development, and quality assurance 📥 Download your free demo now: ➡ Design-Expert Trial Version